血浆治疗与甲泼尼龙联合机械通气治疗重症手足口病的临床效果对比

Comparation of the clinical effect between plasma treatment and methylprednisolone combined with mechanical ventilation in the treatment of severe hand foot and mouth disease

目的:探讨使用血浆治疗与甲泼尼龙联合机械通气治疗重症手足口病的临床疗效。方法:随机选取重症手足口病患者80例,随机分为1组和2组,各40例。1组采用血浆治疗,2组则使用甲泼尼龙联合机械通气治疗,一段时间后观察两组治疗的总有效率,对比其临床治疗疗效。结果:治疗一段时间后,发现1组治疗的临床总有效率远远低于2组,两组的临床总有效率差异有统计学意义,而两组在治疗后症状消失所需要的时间方面也存在差异。结论:相对于利用血浆治疗重症手足口病来说,利用甲泼尼龙联合机械通气治疗的临床效果较好。

Objective:To investigate the clinical efficacy of plasma treatment with methylprednisolone combined with mechanical ventilation in the treatment of severe hand foot mouth disease.Methods:80 patients with severe hand foot and mouth disease were selected as the subjects.They were random Ly divided into the 1 group and 2 group with 40 cases in each.The 1 group were given plasma treatment,and 2 groups were given methylprednisolone combined with mechanical ventilation.After a period of treatment,we observed the total effective of two groups,and compared the clinical curative effect.Results:After a period of treatment,we found that the total effective rate of 1 group was much lower than 2 group,and the difference was statistically significant between two groups.The time of symptoms disappeared after the treatment was different between two groups.Conclusion:Compared with the using of plasma treatment in severe hand foot mouth disease,using methylprednisolone combined with mechanical ventilation can achieve better clinical effect.