阿奇霉素联合特步他林雾化吸入治疗小儿支原体肺炎的疗效分析

Analysis of azithromycin combined with terbutaline atomization inhalation in the treatment of mycoplasma pneumonia in children

目的:探讨阿奇霉素联合特步他林雾化吸入治疗小儿支原体肺炎的疗效。方法:2013年4月-2014年4月收治支原体肺炎小儿102例,按照完全双盲法随机平均分成两组,对照组51例予以常规治疗(红霉素+小儿咳喘灵口服液),研究组51例予以阿奇霉素联合特步他林雾化吸入治疗,观察两组小气道肺功能指标、治疗有效性指标及不良反应情况。结果:治疗后研究组小气道功能指标较对照组有明显改善,且治疗有效性指标情况优于对照组,发生不良反应4例(7.84%),比对照组15例(29.41%)少,比较差异均具统计学意义(P<0.05)。结论:小儿支原体肺炎行阿奇霉素联合特步他林雾化吸入治疗的疗效显著,能快速缓解患者临床症状,不良反应率低。

Objective:To investigate the curative effect of azithromycin combined with terbutaline atomization inhalation in the treatment of mycoplasma pneumonia in children.Methods:102 children with mycoplasma pneumonia were selected from April2013 to April 2014.They were random Ly divided into two groups according to a fully double blind method.51 cases in the control group were treated with conventional therapy(erythromycin+Kechuanling oral liquid).51 cases in the study group were treated with azithromycin combined terbutaline atomization inhalation.We observed the small airway lung function index,treatment effectiveness and adverse reaction of two groups.Results:After the treatment,the small airway function group of the treatment group had significant improvement than that of the control group,and the treatment of validity index is better than that of the control group.4 cases occurred adverse reactions(7.84%),which was less than that of the control group 15 cases(29.41%),and the differences were statistically significant(P<0.05).Conclusion:The effect of azithromycin combined with terbutaline inhalation in the treatment of children with mycoplasma pneumonia is significant.It can rapid relief the clinical symptoms,and the rate of adverse reactions was low.