皮肤恶性肿瘤及癌前病变临床病理探讨

The study of the clinical pathological on skin cancer and precancerous lesions

目的:探讨皮肤恶性肿瘤及癌前病变的发病机制和临床特征。方法:2010年5月-2014年5月收治皮肤恶性肿瘤患者100例,对其临床资料进行回顾性分析,观察皮肤恶性肿瘤及癌前病变的发病机理和临床特征。结果:基底细胞癌、日光性角化、鲍温病是皮肤恶性肿瘤的主要类型;基底细胞癌多发于人体面部,鲍温病多发于人体躯干部位;皮肤恶性肿瘤临床诊断与病理诊断的符合率最高的是Paget病、恶性黑素瘤、鳞状细胞癌。结论:对皮肤恶性肿瘤及癌前病变的发病机制和临床特征进行有效分析,为临床治疗提供重要的参考资料,提高了治愈率。

Objective:To investigate the clinical features and pathogenesis of skin cancer and precancerous lesions.Methods:100patients with skin cancer were selected from May 2010 to May 2014.We retrospectively analyzed their clinical data,and observed the clinical features and pathogenesis of skin cancer and precancerous lesions.Results:Basal cell carcinoma,actinic keratosis and Bowen's disease were the main types of skin malignant tumor;the predilection site of basal cell carcinoma always in human face,and Bowen's disease were common in human torso;the highest coincidence rate of clinical diagnosis and pathological diagnosis of malignant skin tumors were paget disease,malignant melanoma and squamous cell carcinoma.Conclusion:Analysis of the clinical features and pathogenesis of skin cancer and precancerous lesions provides important reference for the clinical treatment,to improve the cure rate.