临床输血不良反应131例回顾分析

Retrospective analysis of adverse transfusion reaction in 131 cases with blood transfusion

目的:回顾分析131例临床输血不良反应的发生情况,为有效预防输血不良反应的发生提供参考。方法:2010年1月-2013年12月收治输血不良反应患者131例,分析引起输血不良反应的原因。结果:在临床接受输血治疗的21 000例患者中,131例发生输血反应,发生率0.62%;男性患者输血不良反应发生率显著高于女性(P<0.05);有输血史患者不良反应发生率显著高于无输血史(P<0.05);单采血小板、冷沉淀、血浆、悬浮少白红细胞输血反应发生率分别为1.54%、0.69%和0.62%和0.48%。结论:加强输血治疗过程中监测,严格掌握临床输血指征,科学合理用血,开展输血新技术、新方法的应用可减少和避免输血不良反应的发生。

Objective:To retrospectively analyze the adverse transfusion reaction in 131 cases with blood transfusion,and to provide a reference for the effective prevention of transfusion adverse reactions.Methods:131 patients with adverse transfusion reaction were selected from January 2010 to December 2013.We analyzed the cause of adverse transfusion reaction.Results:In 21000 cases of clinical blood transfusion in the treatment of patients,131 cases had transfusion reaction,and the incidence was0.62%.In male patients,the adverse reaction rate of blood transfusion was significantly higher than that of females(P<0.05).In the patients with history of blood transfusion,the incidence of adverse reaction was higher than those without a history of blood transfusion(P<0.05).Transfusion reaction rate of apheresis platelet,cryoprecipitate,plasma,little white red cell suspension was respectively 1.54%,0.69% and 0.62% and 0.48%.Conclusion:Strengthening the monitoring of blood transfusion during the treatment,strict controlling of clinical blood transfusion indications,scientific and rational using of blood transfusion,the development of new technologies,and the application of the new method can reduce and avoid the occurrence of adverse transfusion reaction.