螺内酯联合补钾治疗重度周期性麻痹60例疗效观察

Clinical observation of spironolactone combined with potassium supplement in the treatment of 60 cases with severe periodic paralysis

目的:观察螺内酯联合补钾治疗重度周期性麻痹的治疗效果。方法:重度周期性麻痹患者120例随机分为治疗组和对照组。治疗组在常规治疗的基础上加服螺内酯片20 mg口服。对照组给予常规治疗。结果:24 h后复查血钾,治疗组血清钾4.0~4.5 mmol/L,对照组3.0~3.5 mmol/L。结论:螺内酯联合补钾治疗重度周期性麻痹效果显著,值得临床推广与应用。

Objective:To observe the clinical effect of spironolactone combined with potassium supplement in the treatment of severe periodic paralysis.Methods:120 patients with severe periodic paralysis were randomly divided into the treatment group and the control group.The treatment group were treated with 20 mg spironolactone tablet on the basis of the routine treatment.The control group were treated with the routine treatment.Results:The serum potassium of the treatment group was 4.0~4.5 mmol/L and that of the control group was 3.0~3.5 mmol/L in review of the potassium after 24 h.Conclusion:Spironolactone combined with potassium supplement has significant effect in the treatment of severe periodic paralysis.It is worthy of clinical popularization and application.