三苯氧胺联合维生素E与乳康片治疗乳腺增生的临床疗效观察

Clinical effect of tamoxifen combined with vitamin E and rukang tablet in the treatment of hyperplasia of mammary glands

目的:以三苯氧胺联合维生素E与乳康片进行对比,研究2种方法治疗乳腺增生的临床效果。方法:2010年6月-2013年6月收治乳腺增生患者200例,随机分为观察组100例和对照组100例。对照组使用乳康片进行治疗,观察组使用三苯氧胺联合维生素E进行治疗。结果:治疗后,对照组治疗总有效率及不良反应发生率分别为68%和5%;观察组治疗总有效率及不良反应发生率分别为92%和7%。两组总有效率差异具有统计学意义(P<0.05),不良反应发生率差异无统计学意义(P>0.05)。结论:三苯氧胺联合维生素E对于治疗乳腺增生的效果显著,不良反应少,值得临床推广及应用。

Objective:To explore the effect of tamoxifen combined with vitamin E and rukang tablet in the treatment of hyperplasia of mammary glands through comparing the effect of the two kinds of methods.Methods:200 patients with hyperplasia of mammary glands from June 2010 to June 2013 were randomly divided into the observation group(100 cases) and the control group(100 cases).The control group were treated with rukang tablet,and the observation group were treated with tamoxifen combined with vitamin E.Results:After treatment,the total effective rate and the incidence of adverse reactions of the control group were 68% and 5% respectively,and the total effective rate and the incidence of adverse reactions of the observation group were 92% and 7% respectively.There was significant difference of the total effective rate between the two groups(P<0.05).There was no significant difference of the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Tamoxifen combined with vitamin E is effective in the treatment of hyperplasia of mammary glands,and it has few adverse reactions,worthy of clinical popularization and application.