提高新生儿口服给药依从性的比较

Comparison of improving newborn oral medication compliance

目的:提高新生儿口服给药依从性,发挥最大的疗效、减少不良反应。方法:将100例需要口服头孢呋辛酯片的新生儿随机分成两组,观察组和对照组均出生30 min内行早接触早吸吮,观察组医师开出医嘱后对产妇进行用药健康教育和吸吮5 min时口服给药,对照组常规统一时间给药。比较两组新生儿反应:不吸吮、口吹泡泡,恶心、呕吐、溢药等抗拒动作,对下次吸吮的影响等方面的差异。结果:观察组新生儿口吹泡泡、新生儿恶心呕吐、溢药等发生率明显低于对照组(P<0.05)。结论:采用温度37℃12.5%~15%葡萄糖水在餐时喂药新生儿服药依从性效果好,新生儿口吹泡泡、恶心、呕吐、溢药发生少,安静入睡;距离下次主动吸吮所需时间无显著差异。

Objective:To improve newborn oral medication compliance for maximum effect and reduce adverse reaction.Methods:100 newborns with needing oral cefuroxime axetil tablets were randomly divided into two groups.The observation group and the control group were given early contact and sucking in 30 minutes after birth.After the doctors maked out doctor's advice,the observation group were given medical health education for puerpera and oral medication when sucking 5 minutes.The control group administrated a drug at conventional unified time.The neonatal reflex of two group was compared,and the differences of no sucking,blow bubbles,nausea and vomiting, spill medicine and other resisting action impacted on the next time sucking.Results:Neonatal mouth blowing bubbles,neonatal nausea and vomiting and spill medicine were significantly lower than those of the control group(P<0.05).Conclusion:The newborn medication compliance of using the temperature 37 ℃ 12.5%~15% glucose water in meal feeding has good effect.Neonatal mouth blowing bubbles,neonatal nausea and vomiting and spill medicine occur less,and the newborn is quiet sleep.There is no significant difference between distance time needed for active suck next time.