摘要
目的:分析在不孕不育及自然流产患者中染色体异常的发生情况。方法:对2 314例不孕不育及有自然流产史患者行外周血淋巴细胞培养,常规G显带后染色体核型分析。结果:共统计患者2 314例,其中检出染色体核型异常167例,总检出率7.22%。其中,自然流产患者中检出50例异常,检出率8.73%;不孕不育患者中检出122例异常,检出率6.81%。结论:染色体异常是引起不孕不育和自然流产的重要原因之一,在门诊工作中应引起重视。
Objective:To explore the abnormal chromosome in patients with spontaneous abortion and infertility.Methods:2 314 patients with infertility and spontaneous abortion were selected.They were given the peripheral blood lymphocyte culture and chromosome karyotype analysis after conventional G banding.Results:In 2 314 patients,the detection of abnormal chromosome karyotype was in 167 cases,and the total detection rate was 7.22%.Among them,in spontaneous abortion patients,50 cases were abnormal,and the detection rate was 8.73%;in infertility patients,122 cases were abnormal,and the detection rate was 6.81%.Conclusion:Chromosome abnormality was one of the important reasons of infertility and spontaneous abortion.In outpatient service,attention should be paid to it.
基金
伴亚临床甲减的排卵障碍不育诊疗技术的建立和应用(苏州市卫生局科技项目。项目编号:LCZX201302)~~
关键词
染色体异常
不孕不育
自然流产
Chromosome abnormality
Infertility
Spontaneous abortion
