不同年龄段冠心病患者危险因素的对比研究

Comparative study on risk factors of patients with coronary heart disease in different age

目的:研究不同年龄阶段冠心病患者危险因素及其冠状动脉病变临床表现特征。方法:2012年4月-2014年8月收治冠心病患者375例,按照年龄分为A组(青年组75例)、B组(中年组105例)、C组(老年组195例),比较3组间临床资料差异性。结果:3组间在急性心肌梗死、不稳定型心绞痛及心肌梗死3种冠心病类型方面差异均有统计学意义(P<0.05)。在高脂血症家族史方面,差异无统计学意义(P>0.05)。在糖尿病、高血压及冠心病家族史方面,差异均有统计学意义(P<0.05)。3组间在引起冠心病的危险因素中,饮酒、吸烟、糖尿病、肥胖、高舒张压及高收缩压等因素方面差异均有统计学意义(P<0.05)。结论:不同年龄阶段的冠心病患者中,其病变类型、家族史及危险因素差异均存在统计学意义,寻找其规律性与共同点,可为下一步临床治疗提供重要依据。

Objective:To study the risk factors and the clinical features of coronary artery lesions of patients with coronary heart disease in different age stages.Methods:375 patients with coronary heart disease were hospitalized from April 2012 to August2014.They were divided into group A(75 cases in young group),group B(105 cases in middle-aged group)and group C(195 cases in elderly group) according to the age.Clinical data were compared in the three groups.Results:There were significant differences in all the three groups in the aspects of this three types of coronary heart disease of Acute Myocardial Infarction,unstable angina pectoris,and Myocardial Infarction(P<0.05).There were no significant differences in the aspects of family history of hyperlipidemia(P>0.05).There were significant differences in the aspects of family history of diabetes mellitus,hypertension and coronary heart disease(P<0.05).Through the risk factors caused by coronary heart disease in the three groups,the differences were also significant in the aspects of these factors such as drinking,smoking,diabetes mellitus,obesity,high diastolic blood pressure,high systolic blood pressure,and so on(P<0.05).Conclusion:Through the patients with coronary heart disease in different age,there were significant differences in their kinds of lesions,family history and risk factors.The important basis of the next clinical treatment will be provided by finding the regularity and common ground.