原发性肾病综合征合并甲状腺功能异常12例分析

Analysis of 12 cases of primary nephrotic syndrome combined with thyroid dysfunction

目的:分析原发性肾病综合征(PNS)患者血清甲状腺激素的变化,探讨其临床意义。方法:对12例PNS患者的甲状腺素水平与12例正常对照组的甲状腺素水平相比较。结果:PNS组FT3、FT4水平明显低于正常对照组,TSH水平明显高于正常对照组,差异具有统计学意义(P<0.05)。结论:原发性肾病综合征患者可出现甲状腺激素水平异常,对其检测有助于判断病情及预后。

Objective:We analyzed the changes of serum thyroid hormone in patients with primary nephrotic syndrome(PNS),in order to discuss its clinical significance.Methods:We compared the level of thyroid hormones in 12 patients with PNS and the level of thyroid hormone in 12 cases of normal control group.Results:The FT3 and FT4 levels of the PNS group were significantly lower than those of the normal control group,and the TSH levels were significantly higher than that of the normal control group, with significant difference(P<0.05).Conclusion:The patients with primary nephrotic syndrome can occur abnormal thyroid hormone levels.Its detection may help to judge the severity and prognosis.