影响ICU慢性阻塞性肺疾病患者机械通气时间的各种因素

Various factors of the influence of mechanical ventilation time in patients with chronic obstructive pulmonary disease in ICU

目的:观察影响ICU慢性阻塞性肺疾病患者机械通气时间的各种因素。方法:2012年4月-2014年4月收治慢性阻塞性肺疾病患者72例,使用机械通气进行治疗,按照机械通气的时间将其分成A组、B组、C组,每组24例,A组通气时间≤7 d,B组8~14 d,C组>14 d,对比插管前后,影响3组患者机械通气时间的各种因素。结果:C组的年龄、心率、消化道出血例数、相关性肺炎例数、血压下降例数、APACHEⅡ评分、VAP均高于A组与B组,并且血清白蛋白、前白蛋白、Pa O2/Fi O2等数值都低于A组与B组,差异具有统计学意义(P<0.05)。结论:影响ICU慢性阻塞性肺疾病患者机械通气时间的因素有很多,包括插管前与插管后多方面因素,应引起医护人员的高度重视。

Objective:To observe the various factors of the influence of mechanical ventilation time in patients with chronic obstructive pulmonary disease in ICU.Methods:72 patients with chronic obstructive pulmonary disease in ICU were selected from April 2012 to April 2014.They were treated by mechanical ventilation.According to the mechanical ventilation time,they were divided into A group,B group,C group with 24 cases in each.The ventilation time of A group was less than or equal to 7 days;B group was 8 to 14 days;C group was more than 14 days.The various factors of the influence of mechanical ventilation time of three groups were compared before and after intubation.Results:The age,heart rate,the number of gastrointestinal bleeding,the number of ventilator-associated pneumonia,the number of blood pressure fall,APACHE Ⅱ score,VAP of patients in C group were all higher than those of A group and B group,and serum albumin,prealbumin,Pa O2/Fi O2 and other values were lower than those of A group and B group.The difference was statistically significant(P<0.05).Conclusion:The factors of the influence of mechanical ventilation time in patients with chronic obstructive pulmonary disease in ICU are many,including many factors before intubation and after intubation,which much attention should be paid by medical personnel.