不同剂量奥美拉唑治疗非静脉曲张上消化道出血临床观察

Clinical observation of different doses of omeprazole in the treatment of non variceal upper digestive tract hemorrhage

目的:探讨分析不同剂量奥美拉唑治疗非静脉曲张上消化道出血的临床疗效。方法:2009年2月-2014年3月收治非静脉曲张上消化道出血患者134例,回顾性分析其临床资料。结果:治疗后,治疗组总有效率94.03%,高于对照组的80.6%,差异具有统计学意义(P<0.05);其止血时间、住院时间以及再出血率均低于对照组,差异均具有统计学意义(P<0.05);两组不良反应发生率相比差异则无统计学意义(P>0.05)。结论:奥美拉唑治疗非静脉曲张上消化道出血的临床疗效显著,值得在临床推广应用。

Objective:To explore and analyze of clinical effects of different doses of omeprazole in the treatment of non variceal upper digestive tract hemorrhage.Methods:134 patients with non variceal upper digestive tract hemorrhage were selected from February 2009 to March 2014.The clinical data were retrospectively analyzed.Results:After treatment,the total effective rate of the treatment group was 94.03%,which was higher than 80.6% of the control group,and the difference was statistically significant(P<0.05).The hemostasis time,hospitalization time and bleeding rate again were lower than those of the control group,and the difference was statistically significant(P<0.05).The adverse reaction rates of two groups were compared with no significant difference(P>0.05).Conclusion:Omeprazole in the treatment of non variceal upper digestive tract hemorrhage has significant clinical effect.It is worth to popularize in the clinical application.