米素前列醇在早早孕人工流产中的临床应用

Clinical application of misoprostol in very-early pregnancy artificial abortion

目的:探讨米索前列醇在早早孕人工流产中应用的可行性、有效性及安全性。方法:2014年1-6月收治早早孕孕妇60例。A组30例,术前2 h将米索前列醇600μg空腹口服;B组30例,术前2 h将米索前列醇600μg放置阴道后穹隆。比较两组不良反应、术中出血量、宫颈扩张度;手术时间、术后阴道出血天数。结果:A组宫颈扩张效果、手术时间优于B组,其差异有统计学意义(P<0.01);A、B两组在不良反应、术中出血量及术后阴道出血量比较,其差异均无统计学意义(P>0.05)。结论:口服米索前列醇用于早早孕人工流产是切实可行的。

Objective:To explore the feasibility,efficacy and safety of the application of misoprostol in very-early pregnancy artificial abortion.Methods: 60 cases in early pregnancy pregnant women of our hospital from January to June 2014 were selected. A group of 30 cases, preoperative 2 h misoprostol 600 μg oral on an empty stomach.B group of 30 cases, preoperative 2 h placing misoprostol 600 μg after vaginal vault.We compared adverse reactions, intraoperative blood loss,the degree of cervical dilation, operation time,postoperative vaginal bleeding of two groups.Results: the cervical dilation effect and operation time of group A was better than that of group B,and the difference was statistically significant (P<0.01).The differences of adverse reactions, intraoperative blood loss and postoperative vaginal haemorrhage amount of two groups were not statisticallt significant(P>0.05). Conclusion:The oral group is feasible for very-early pregnancy artificial abortion.