慢快综合征患者植入起搏器后参数调整对预后的影响分析

Impact analysis of adjustment of the parameters on the prognosis of slow fast syndrome patients with pacemaker

目的:分析慢快综合征患者植入起搏器后参数调整对预后的影响。方法:2011年7月-2014年7月收治慢快综合征患者68例,随机分为对照组和研究组各42例,两组均植入起搏器,对照组起搏心率设置为65次/min,研究组设置为55次/min,比较两组相关参数、生活质量SF-36量表评分及心房纤颤发生率。结果:研究组Ap、Vp均低于对照组,且LVEDD、LVEF改善情况均优于对照组,有统计学意义(P<0.05);研究组血脑钠钛浓度(BNP)显著低于对照组,差异有统计学意义(P<0.05);研究组SF-36量表评分显著高于对照组,差异有统计学意义(P<0.05);研究组心房纤颤发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:慢快综合征患者植入起搏器后,适当地降低起搏心率可有效降低BNP,从而降低心房纤颤发生率,改善患者远期预后。

Objective:To explore the impact of adjustment of the parameters on the prognosis of slow fast syndrome patients with pacemaker.Methods:68 patients with slow fast syndrome were selected from July 2011 to July 2014.They were randomly divided into the control group and the study group with 42 cases in each group.Two groups were implanted pacemaker.In the control group,pacing rate was 65 times/min;in the study group,pacing rate was 55 times/min.We compared the relevant parameters,life quality SF-36 scale score and incidence of atrial fibrillation.Results:In the study group,Ap,Vp were lower than that of the control group,and LVEDD,LVEF improvement were better than that of the control group,and the difference was statistically significant(P<0.05);in the study group,BNP was significantly lower than that of the control group,and the difference was statistically significant(P<0.05);in the study group,SF-36 scale score was significantly higher than the control group,and the difference was statistically significant(P<0.05);in the study group,atrial fibrillation rate was significantly lower than that of control group,and the difference was statistically significant(P<0.05).Conclusion:In slow fast syndrome patients after implantation of pacemaker,reducing the rate of pacing appropriately can effectively decrease the BNP,so as to reduce the incidence of atrial fibrillation and improve the prognosis of the patients.