中西医结合治疗慢性阻塞性肺疾病疗效观察

The curative effect observation of combination of Chinese traditional and western medicine in the treatment of chronic obstructive pulmonary disease

目的:探讨中西医结合治疗慢性阻塞性肺疾病(COPD)的临床疗效。方法:2013年2月-2014年8月收治COPD患者80例,随机分成观察组和对照组各40例,对照组按照吸氧、抗感染、祛痰、解痉平喘的治疗原则,给予盐酸氨溴索片30 mg/次,3次/d,头孢拉定3.0 g静滴,2次/d,急性期雾化吸入异丙托溴铵溶液2 m L+硫酸沙丁胺醇溶液2 m L,3次/d,20 min/次。观察组在对照组的基础上加用抗感染汤治疗。结果:两组患者治疗前MMEF和FEV1比较差异无统计学意义(P>0.05),治疗后两组均明显改善,与治疗前比较差异有统计学意义(P<0.05),观察组明显优于对照组,两组治疗后比较差异有统计学意义(P<0.05)。观察组临床控制12例,显效24例,有效2例,无效2例,总有效率95.0%;对照组临床控制5例,显效16例,有效10例,无效9例,总有效率77.5%,两组比较差异有统计学意义(P<0.05)。结论:中西医结合治疗COPD疗效显著,值得推广。

Objective:To explore the curative effect of combination of Chinese traditional and western medicine in the treatment of chronic obstructive pulmonary disease.Methods:80 cases of COPD patients were selected from February 2013 to August 2014.They were randomly divided into the observation group and the control group with 40 cases in each group.In accordance with the oxygen,anti infection,expectorant,antispasmodic asthma treatment principle,the control group was given ambroxol hydrochloride tablets 30 mg/time,3 times/day,Cefradine 3.0 g intravenous drip,2 times /day,in the acute phase,inhalation of ipratropium bromide solution 2 m L + salbutamol sulfate solution 2 m L,3 times/day,20 min/time.The observation group were given the anti infection decoction on the basis of the control group.Results:Before treatment,we compared the MMEF and FEV1 of the two groups,there was no significant difference(P>0.05);after treatment,two groups were significantly improved,compared with that before treatment,and the difference was statistically significant(P<0.05);the observation group was obviously better than the control group, and compared the two groups after treatment, the difference was statistically significant(P<0.05).In the observation group,12 cases had clinical control;24 cases were markedly effective;2 cases were effective;2 cases were invalid;the total effective rate was 95%.In the control group,5 cases had clinical control;16 cases were markedly effective;10 cases were effective;9 cases were invalid;the total efficiency was 77.5%;compared the two groups,the difference was statistically significant(P<0.05).Conclusion:The curative effect of combination of Chinese traditional and western medicine in the treatment of chronic obstructive pulmonary disease was significant.It was worthy of promotion.