C反应蛋白在严重肝病继发感染诊治中的价值分析

Value analysis of C reactive protein in the diagnosis and treatment of severe liver disease complicated with infection

目的:探析C反应蛋白(CRP)在严重肝病患者续发感染诊治中的应用及其临床价值。方法:收治病毒性肝炎出现继发性感染患者86例,所有患者均采用舒巴坦以及头孢派酮进行联合治疗。入院后第2天以及发生继发感染后第3天进行采血,比较不同时期患者血清中CRP水平的不同。结果:重型肝炎以及肝硬化失代偿患者感染前后以及感染后和经治疗后,CRP之间的差异有统计学意义(P<0.05)。结论:重型肝炎和肝硬化失代偿患者的血清C反应蛋白可以有效反映出患者的感染程度,让肝病患者的继发感染情况得以早期发现,避免疾病的进一步发展。同时,还需要严密监测患者的CRP水平,对抗生素以及各种药物的应用情况予以调整,为患者继发感染的临床治疗提供指导,预估患者的预后情况,可在严重肝病患者的临床诊治过程中发挥重要作用,临床价值较大。

Objective:To explore the application and its clinical value of C reactive protein in the diagnosis and treatment of severe liver disease complicated with infection.Methods:86 patients with viral hepatitis complicated with infection were selected. All patients were treated with sulbactam combined with cefoperazone.Blood was collected in second days after admission and third days after secondary infection.We compared patients with serum CRP level in different period.Results:In severe hepatitis and decompensated liver cirrhosis patients,before and after infection and after infection and before and after treatment,there were significant differences in CRP,and the difference was statistically significant(P<.05).Conclusion:In severe hepatitis and decompensated liver cirrhosis patients,serum C reactive protein can effectively reflect the degree of infection in patients with liver disease.Patients with secondary infection can be found early,to avoid the further development of the disease.At the same time,we also need to closely monitor patients with CRP level,adjust the antibiotics and application of various drugs,and provide guidance for clinical treatment of patients with secondary infection,predict the prognosis of patients.It can play an important role in clinical diagnosis and treatment of patients with severe liver disease,and the clinical value is larger.