小儿支气管哮喘与肺炎支原体感染的关系

The relationship between children bronchial asthma and mycoplasma pneumoniae infection

目的:探讨小儿支气管哮喘与肺炎支原体(MP)感染的关系,从而为小儿支气管哮喘的治疗方案提供指导依据。方法:2009年6月-2013年6月收治呼吸道感染并支气管哮喘患儿100例作为观察组,另外100例呼吸道感染患儿作为对照组,通过血清学检查MP-Ig M,确定患儿肺炎支原体感染的情况。呼吸道感染并支气管哮喘组有48例MP-Ig M阳性,将这48例患儿随机分为两组,一组按常规支气管哮喘治疗,另一组在常规治疗的基础上,加用阿奇霉素抗肺炎支原体感染治疗,比较两组患儿的治疗效果。结果:对照组的MP-Ig M阳性率20%,观察组的MP-Ig M阳性率48%,差异有统计学意义(P<0.05)。常规支气管哮喘治疗组有效率37.5%,常规支气管哮喘治疗加阿奇霉素治疗组有效率83.3%,差异有统计学意义(P<0.05)。结论:小儿肺炎支原体感染与支气管哮喘关系密切,对支气管哮喘患儿应常规检测肺炎支原体感染情况。阳性者在按哮喘常规治疗同时予抗肺炎支原体感染治疗,能提高疗效。

Objective:To discuss the relationship between children bronchial asthma and mycoplasma pneumoniae infection,so as to provide guidance for the treatment schedule of children bronchial asthma.Methods:100 bronchial asthma children with respiratory tract infection were selected from June 2009 to June 2013 as the observation group.100 children with respiratory tract infection were as the control group.The situation of children mycoplasma pneumoniae infection was ensured by serological examination MP-IgM.48 cases of MP-IgM in the respiratory tract infection with bronchial asthma group were positive.The 48 children were randomly divided into two groups.One group was treated with conventional treatment of bronchial asthma,and another group was treated with azithromycin against mycoplasma pneumoniae infection on the basis of conventional treatment.The treatment effects of two groups were compared.Results:The MP-IgM positive rate of the control group was 20% ;the MP-IgM positive rate of the observation group was 48% ;the difference was statistically significant(P<0.05).The effective rate of the conventional bronchial asthma treatment group was 37.5%;the effective rate of the conventional bronchial asthma treatment and azithromycin treatment group was 83.3%;the difference was statistically significant(P<0.05).Conclusion:The relationship between the children mycoplasma pneumoniae infection and bronchial asthma is close,and the children with bronchial asthma should be given routine detection of mycoplasma pneumoniae infection situation.The positive patients are given against pneumonia mycoplasma infection according to the asthma conventional treatment at the same time,which can enhance the curative effect.