普罗帕酮和胺碘酮治疗阵发性室上性心动过速的临床分析

Clinical analysis of propafenone and amiodarone in the treatment of paroxysmal suproventricular tachycardia

目的:探讨分别运用普罗帕酮和胺碘酮治疗阵发性室上性心动过速的临床效果。方法:2010年11月-2014年7月收治阵发性室上性心动过速患者64例,随机分为观察组和对照组,各32例。对照组和观察组分别采用普罗帕酮和胺碘酮进行治疗,比较两组的治疗效果。结果:观察组转复时间明显长于对照组,不良反应率明显低于对照组,组间比较差异均具有统计学意义(P<0.05)。观察组临床总有效率(87.50%)同对照组(90.63%)相比差异无统计学意义(P>0.05)。结论:在阵发性室上性心动过速的临床治疗中,普罗帕酮和胺碘酮均有良好的治疗效果,但普罗帕酮起效更快,胺碘酮的安全性更高。

Objective:To explore the clinical effect of propafenone and amiodarone used respectively in the treatment of paroxysmal suproventricular tachycardia.Methods: 64 cases of paroxysmal suproventricular tachycardia were selected from November 2010 to July 2014.They were divided into the observation group and the control group with 32 cases in each.The control group and the observation group were treated with propafenone and amiodarone respectively.We compared the therapeutic effect of the two groups.Results:The converting time of the observation group was obviously higher than that of the control group,and the adverse reaction rate was significantly lower than that of the control group.The differences between the two groups were statistically significant(P<0.05).The total clinical effective rate of the observation group(87.50%) was compared with that of the control group(90.63%),and there was no statistically significant difference(P>0.05).Conclusion:Propafenone and amiodarone in the treatment of paroxysmal suproventricular tachycardia had good treatment effect,but amiodarone had faster effect and higher safety.