摘要
目的:考察沈阳地区小儿肺炎支原体(Mycoplasma pneumomae,MP)感染及耐药情况,为临床抗菌药物选择提供依据。方法:2012年9月-2014年9月收治小儿肺炎患者1 079例,采血进行MP-IGM检测,采集咽拭子进行MP培养及药敏试验。结果:1 079例小儿肺炎患者MP培养阳性327例,阳性率30.3%,MP-IGM阳性388例,阳性率36.0%,差异具有统计学意义(P<0.05)。分离出的MP对红霉素、罗红霉素及乙酰螺旋霉素耐药率较高,而对加替沙星及司帕沙星等氟喹诺酮类药物普遍敏感。结论:建议经验型用药同时尽早采集咽拭子做MP培养及药敏试验,根据药敏结果调整用药,高度警惕耐药肺炎支原体肺炎的存在,避免不合理使用抗生素。
Objective:To study the infantile pneumonia mycoplasma infection and drug resistance in Shenyang area,and provide the basis for the clinical selection of antibacterial drugs.Methods:1 079 cases of infantile pneumonia patients were selected from September 2012 to September 2014.They were given MP-IGM detected by blood.Throat swab was collected for MP culture and drug sensitivity test.Results:In 1 079 cases of pediatric patients with pneumonia,327 cases of MP culture were positive,and the positive rate was 30.3%;388 cases of MP-IGM were positive,and the positive rate was 36%;the difference had statistical significance(P<0.05).MP resistance rate was higher for erythromycin,roxithromycin and acetyl spiramycin,which was sensitive to gatifloxacin and sparfloxacin and other fluoroquinolones drugs.Conclusion:We recommend the use of experience medicine,at the same time,we proposed as early as the throat swabs collect for MP culture and drug sensitive test,and we adjusted medication according to the results of drug sensitivity,we should be alert to the presence of drug resistance of mycoplasma pneumoniae,and avoided the irrational use of antibiotics.
出处
《中国社区医师》
2015年第7期16-17,20,共3页
Chinese Community Doctors
关键词
肺炎
咽拭子
肺炎支原体
药敏试验
Pneumonia
Throat swab
Mycoplasma pneumoniae
Drug sensitivity test
