过氧化苯甲酰联合多磺酸黏多糖治疗寻常痤疮疗效观察

Clinical efficacy observation of benzoyl peroxide combining with mucopolysaccharide polysulfate in the treatment of vulgaris acne

目的:观察过氧化苯甲酰联合多磺酸黏多糖治疗寻常痤疮的临床疗效。方法:2011年1月-2014年3月收治寻常痤疮患者126例,随机分为两组。A组采用多磺酸黏多糖乳膏联合过氧化苯甲酰凝胶治疗,B组采用过氧化苯甲酰凝胶,疗程均8周,比较两组的治疗效果。结果:A组总有效率80.95%,B组总有效率63.49%。A组褐红斑、结节及瘢痕的遗留少于B组。两组患者治疗的总有效率及预后比较,差异均有统计学意义(P<0.05)。结论:过氧化苯甲酰凝胶联合多磺酸黏多糖乳膏治疗寻常痤疮效果较好,并能有效改善预后。

Objective:To observe the therapeutic effects of benzoyl peroxide combining with mucopolysaccharide polysulfate on vulgaris acne.Methods:126 patients with mild to moderate acne were randomized divided into two groups.The group A was treated with benzoyl peroxide gel combined mucopolysaccharide polysulfate cream.The group B was only treated with benzoyl peroxide gel,the treatment course was 8 weeks,and the therapeutic effects of the two groups were comared.Results:The total effective rate of the group A was 80.95% and that of the group B was 63.49%.The remains of erythema or nodule or scar in group A were less than that of the group B.There were differences of the total effective rate and the prognosis between the two groups(P<0.05). Conclusion:Benzoyl peroxide gel combined with mucopolysaccharide polysulfate cream in the treatment of vulgaris acne was more effective and made better prognosis.