阿奇霉素治疗小儿支原体肺炎的临床疗效观察

Clinical curative effect observation of azithromycin in the treatment of mycoplasma pneumonia in children

目的:观察阿奇霉素治疗小儿支原体肺炎的临床疗效及安全性。方法:将110例支原体肺炎患儿随机均分为观察组和对照组,观察组在常规治疗基础上给予阿奇霉素治疗,对照组在常规治疗基础上给予红霉素治疗,对两组的临床疗效和不良反应进行比较。结果:观察组总有效率95.1%,对照组总有效率72.73%,差异具有统计学意义(P<0.05)。观察组退热时间、咳嗽消失时间、肺部啰音消失时间均明显短于对照组,差异有统计学意义(P<0.05)。两组不良反应比较差异无统计学意义(P>0.05)。结论:阿奇霉素治疗小儿支原体肺炎具有疗效好、见效快、不良反应少等优点,可显著缩短患儿症状消失时间,缩短住院时间,值得临床推广。

Objective:To observe the clinical curative effect and safety of azithromycin in the treatment of mycoplasma pneumonia in children.Methods:110 children with mycoplasma pneumonia were randomly divided into the observation group and the control group.The observation group was given azithromycin treatment on the basis of conventional treatment,and the control group was given erythromycin treatment on the basis of conventional treatment.The clinical curative effects and adverse reactions were compared in two groups.Results:In the observation group,the total effective rate was 95.1%;that of the control group was 72.73%;the difference was statistically significant(P<0.05).In the observation group,the antifebrile time,cough disappeared time, pulmonary rales disappearance time of children were significantly shorter than those of the control group,and the difference was statistically significant(P<0.05).The adverse reactions of two groups were compared,the difference was no statistically significant(P>0.05).Conclusion:Azithromycin intravenous infusion in the treatment of mycoplasma pneumonia in children has the advantages,such as good curative effect,quick effect,less adverse reaction.It can significantly shorten the disappearance time of symptoms,and shorten the hospitalization time.It is worth the clinical promotion.