老年性药源性糖尿病低血糖昏迷的临床疗效分析

Curative effect analysis of senile drug-induced diabetes with hypoglycemic coma

目的:探讨老年性药源性糖尿病低血糖昏迷的临床诊治方法及安全性,意在提高老年性药源性糖尿病低血糖昏迷患者的临床疗效。方法:2012年8月-2014年8月收治老年性药源性糖尿病低血糖昏迷患者80例,回顾性分析临床资料。结果:经过治疗后,60例患者治疗20 min^2 h后意识清醒。20例患者在给予血糖纠正30 min后仍然处于昏迷状态,给予含量20%的甘露醇、脑细胞营养剂以及氢化可的松静脉滴注后,有显著好转。12例患者出现明显反应迟钝及记忆力减退的情况。1例患者自身伴发肾功能不全,经抢救无效后死亡。结论:老年性糖尿病患者非常容易诱发药源性低血糖昏迷等并发症,医护人员应当加强患者的生命体征监测与预防措施,以此降低并发症发生率,提高临床治愈率。

Objective:To explore the clinical diagnosis and treatment methods and security of senile drug-induced diabetes with hypoglycemic coma to improve the clinical curative effect of senile patients with drug-induced diabetes combined hypoglycemic coma.Methods:The clinical data of 80 senile patients with drug-induced diabetes combined low blood sugar coma from August 2012 to August 2014 were analyzed retrospectively.Results:After treatment,60 patients had conscious after the treatment for 20 min^2 h.20 patients were still in coma after correcting blood sugar for 30 min and had improved significantly after intravenous drip of 20% mannitol,brain cells nutrients and hydrocortisone.12 patients had unresponsive and memory loss.1 patient had renal insufficiency and died after invalid rescue.Conclusion:Senile diabetes patients had the complications such as drug-induced hypoglycemia coma easily and the medical personnel should strengthen the monitoring of patient's vital signs and preventive measures in order to reduce the incidence of complications,improving the clinical cure rate.