氧疗对稳定期COPD患者肺功能及动脉血气的影响

Influence of oxygen therapy on the pulmonary function and arterial blood gas of COPD patients in stable stage

目的:总结氧疗对稳定期慢性阻塞性肺疾病(COPD)患者肺功能及动脉血气的影响情况。方法:2013年4月-2014年11月收治稳定期COPD患者70例,随机分成观察组和对照组各35例,对照组给予常规治疗方法,观察组在对照组的基础上增加氧疗,氧气流量控制在2 L/min,连续氧疗10 h,每天坚持氧疗1次。结果:两组患者治疗前MMEF和FEV1比较差异无统计学意义(P>0.05);治疗后两组均明显改善,与治疗前比较差异有统计学意义(P<0.05);观察组明显优于对照组,两组治疗后比较差异有统计学意义(P<0.05);两组患者治疗前Pa O2和Pa CO2比较差异无统计学意义(P>0.05);治疗后,观察组明显优于对照组,两组比较差异有统计学意义(P<0.05)。观察组临床控制12例,显效21例,有效1例,无效1例,总有效率97.1%;对照组临床控制4例,显效14例,有效10例,无效7例,总有效率80.0%,两组比较差异有统计学意义(P<0.05)。结论:稳定期COPD患者增加氧疗可以明显改善患者动脉血气,提高血氧饱和度,临床疗效显著,值得推广。

Objective:To summarize the influence of oxygen therapy on the pulmonary function and arterial blood gas of COPD patients in stable stage.Methods:70 COPD patients in stable stage were selected from April 2013 to November 2014.They were randomly divided into the observation group and the control group with 35 cases in each.The control group was given routine treatment method,and the observation group was given oxygen therapy on the basis of the control group.The oxygen flow was controled in 2 L/minutes,the continuous oxygen therapy 10 hours,insist on oxygen cure 1 time one day.Results:MMEF and FEV1 before treatment of patients in two groups were compared with no statistical significance(P>0.05);the two groups were significantly improved after treatment,it was compared with before treatment with statistical significance(P<0.05);the observation group was significantly better than the control group,the two groups after treatment were compared with statistically significant(P<0.05).PaO2 and PaCO2 before treatment of patients in two groups were compared with no statistical significance(P>0.05);after treatment,the observation group was significantly better than the control group,the two groups were compared with statistically significant(P<0.05).In the observation group,12 cases were clinical control,21 cases were excellent,1 case was effective,1 case was invalid,the total effective rate was 97.1%.In the control group,4 cases were clinical control,14 cases were excellent,10 case was effective,7 case was invalid,the total effective rate was 80.0%.The two groups were compared with statistical significance(P<0.05).Conclusion:COPD patients in stable stage increased oxygen therapy can significantly improve the arterial blood gas of patients,improve blood oxygen saturation,the curative effect is obvious.It is worth promoting.