ICU重症患者严重低血糖临床分析及对预后的影响

Clinical analysis of severe hypoglycemia in patients in ICU and its effect on prognosis

目的:对ICU重症患者严重低血糖进行临床分析,探讨其对预后的相关影响。方法:2013-2014年收治严重低血糖患者120例,60例早期严重低血糖,60例延迟严重低血糖,停止强化胰岛素控制,以50%葡萄糖注射液60 m L静脉注射,再以50%葡萄糖注射液50 m L静脉持续泵入,10 m L/h处置严重低血糖患者。对患者一般资料、APACHE评分、病史、预后等内容进行记录,并对其2种疾病的发生几率及预后影响进行探讨。结果:重症患者发生早期严重低血糖与延迟严重低血糖发生率差异无统计学意义(P>0.05);早期严重低血糖患者的APACHE评分、死亡率要高于延迟严重低血糖,差异有统计学意义(P<0.05)。结论:重症患者出现严重低血糖能反映出患者病情发展情况,且早期严重低血糖对患者生命安危造成了威胁,其死亡率要显著高于延迟严重低血糖,在临床中,患者应引起重视,及时加以治疗。

Objective:To explore the clinical analysis of severe hypoglycemia in patients in ICU and its effect on prognosis. Methods:120 patients with severe hypoglycemia were selected from 2013 to 2014.60 cases of patients were early severe hypoglycemia,58 cases of patients were delayed severe hypoglycemia,improved glucose control was stopped,50% GS 60 mL with intravenous injection,and then 50% GS 50 mL with continuous intravenous pumping,10 mL/hour were used for the treatment of patients with severe hypoglycemia.We recorded the general information,medical history,APACHE score,prognosis and so on,and investigated the occurrence probability and its effect on prognosis of two kinds of diseases.Results:In severe cases,the incidence of difference between early severe hypoglycemia and delayed severe hypoglycemia was small,there was no statistical significance(P>0.05);APACHE score,mortality of early severe hypoglycemia was higher than that of delayed severe hypoglycemia,the difference was statistically significant(P<0.05).Conclusion:In severe cases,severe hypoglycemia symptoms can reflect the patients with disease development,and early severe hypoglycemia posed a threat to the lives of patients,the mortality rate is significantly higher than that of delayed severe hypoglycemia,in clinical practice,patients should be paid attention to and be treated in time.