米索前列醇用于预防经阴道自然分娩产后出血的临床分析

Clinical analysis of misoprostol for the prevention of postpartum hemorrhage induced by transvaginal natural delivery

目的:探讨米索前列醇预防经阴道自然分娩产后出血的临床疗效以及不良反应。方法:将100例自然分娩产妇按随机数列法分为对照组与观察组,每组50例。观察组采用米索前列醇片治疗,对照组采用缩宫素治疗。对比两组产后24 h出血量、产后出血发生率、宫腔积血发生率与不良反应发生率。结果:两组产后24 h出血量、宫腔积血发生率、不良反应发生率均存在显著差异,差异具有统计学意义(P<0.05)。结论:米索前列醇预防经阴道自然分娩产后出血疗效确切,能够明显降低患者产后出血量,降低术后不良反应。

Objective:To explore the clinical curative effect and adverse reactions of misoprostol for the prevention of postpartum hemorrhage induced by transvaginal natural delivery.Methods:According to random sequence method,100 cases of puerpera with natural delivery were divided into the control group and the observation group,with 50 cases in each group.The observation group were treated with misoprostol tablets and the control group were treated with oxytocin.The postpartum 24 h blood loss,incidence of postpartum hemorrhage,uterine hemorrhage rate and incidence of adverse reactions of the two groups were compared.Results:There were statistically significant differences of the postpartum 24 h blood loss,uterine hemorrhage rate and incidence of adverse reactions between the two groups(P<0.05).Conclusion:Misoprostol for the prevention of postpartum hemorrhage induced by transvaginal natural delivery had curative effect,which could reduce the postpartum haemorrhage amount of patients significantly and reduce the postoperative adverse reactions.