癌症患者红细胞分布宽度和其他的血红细胞参数与静脉血栓栓塞和死亡风险的相关性

Red cell distribution width and other red blood cell parameters with venous thromboembolism and mortality risk of patients with cancer

目的:分析癌症患者红细胞分布宽度(RDW)及其他血红细胞(RBC)参数与静脉血栓栓塞风险和死亡率的相关性。方法:检测1 840例癌症患者的RBC参数,主要研究结果是静脉血栓栓塞(VTE)症状的发生、次要结局是随访2年死亡。结果:高RDW(>16%)及其他血红细胞参数与VET风险无明显关联。高RDW增加死亡风险。结论:RDW及其他RBC参数与癌症患者VET风险无独立相关,而高RDW是癌症患者生存较差的独立预示因素。

Objective:To analyze the correlation of red cell distribution width(RDW) and other red blood cell(RBC) parameters with venous thromboembolism risk and mortality rate in patients with cancer.Methods:RBC parameters of 1840 patients with cancer were detected.The main research result was the occurrence of venous thromboembolism(VTE) symptoms,and the secondary outcome was followed up for 2 years of death.Results:High RDW(more than 16%) and other red blood cells parameters were not associated with VET risk.High RDW increased the mortality risk.Conclusion:RDW and other RBC parameters have no independent correlation with VET risk of patients with cancer.And high RDW was a independent predictor of poor survival in patients with cancer.