儿童中枢神经系统感染脑脊液降钙素原测定的意义

Significance of cerebrospinal fluid procalcitonin determination of children's central nervous system infection

目的:探讨中枢神经系统感染患儿脑脊液降钙素原(PCT)变化的临床意义。方法:采用酶联荧光分析技术检测64例中枢神经系统感染患儿脑脊液降钙素原,25例无神经系统疾病且需腰麻的外科手术患儿作为对照组。结果:化脓性脑膜炎患者脑脊液中的PCT阳性率高于病毒性脑膜炎和对照组(P<0.05)。结论:患儿脑脊液PCT的检测可有助于鉴别中枢神经系统感染性质,对儿童中枢感染性疾病诊治具有重要意义。

Objective:To explore the clinical significance of cerebrospinal fluid procalcitonin change of children with central nervous system infection.Methods:The cerebrospinal fluid procalcitonins of 64 children with central nervous system infection were detected by enzyme-linked fluorescent analysis technology.25 cases of surgical operation children needing lumbar anesthesia and without nervous system diseases were as the control group.Results:The procalcitonin positive rate in cerebrospinal fluid of patients with suppurative meningitis was higher than that of virus meningitis and the control group(P<0.05).Conclusion:The children’s cerebrospinal fluid procalcitonin determination can help to identify the central nervous system infection properties.It has important significance on the diagnosis and treatment of children’s central nervous system infection.