小儿肝硬化临床特点及诊治

Clinical characteristics,diagnosis and treatment of children liver cirrhosis

目的:探究小儿肝硬化的临床特点及其诊治。方法:对40例小儿肝硬化的病因、临床特点、治疗和转归进行总结和分析,并与同时期的成人肝硬化进行对比。结果:病毒性小儿肝硬化25例(62.5%),其中乙型肝炎20例;其次是胆汁性肝硬化6例(15.0%),前瞻性静脉海绵样变性4例(10.0%)。小儿肝硬化患者的主要症状为乏力、浮肿,其主要体征为肝脾腹水、肿大、黄疸等。结论:实验室检查对小儿肝硬化并没有特异性的诊断价值;结合小儿的生理学特点,尽早诊断与治疗是防止和逆转该病的关键。

Objective:To explore the clinical characteristics,diagnosis and treatment of children liver cirrhosis.Methods:The etiology,clinical characteristic,treatment and outcome of 40 cases of children liver cirrhosis were summarized and analyzed,and they were compared with adult liver cirrhosis in the same period.Results:25 cases(62.5%) were viral children liver cirrhosis,including 20 cases were hepatitis B.Followed by 6 cases(15%) were biliary cirrhosis,4 cases(10.0%) were prospective vein spongy degeneration.The main symptoms of patients with children liver cirrhosis were fatigue and edema.The main signs were liver and spleen ascites,enlargement,jaundice and so on.Conclusion:The laboratory examination has no specific diagnostic value in children liver cirrhosis.Combined with the physiological features of children,early diagnosis and treatment are the keys to prevent or reverse the disease.