盐酸哌罗匹隆治疗精神分裂症的临床疗效观察

Observation of the clinical efficacy of perospirone hydrochloride in the treatment of schizophrenia

目的:探讨盐酸哌罗匹隆治疗精神分裂症的临床疗效。方法:收治精神分裂症患者110例,随机分为对照组和观察组,各55例,对照组采用阿立哌唑治疗,观察组采用盐酸哌罗匹隆治疗,比较治疗效果。结果:两组患者的不良反应发生率、总有效率以及PANSS评分差异无统计学意义(P>0.05)。相对于治疗之前,两组患者的PANSS评分在治疗之后显著下降(P<0.05)。结论:盐酸哌罗匹隆治疗精神分裂症有良好的治疗效果,而且不会出现明显的不良反应。

Objective:To explore the clinical efficacy of perospirone hydrochloride in the treatment of schizophrenia.Methods:110 patients with schizophrenia were selected.They were randomly divided into the control group and the observation group with 55 cases in each group.The control group was treated with aripiprazole,and the observation group was treated with perospirone hydrochloride.We compared the treatment effect.Results:The difference was not significant in incidence of adverse reaction,and the total efficiency rate and PANSS score of two groups(P>0.05).Compared with before treatment,PANSS score in two groups after treatment was significantly decreased(P<0.05).Conclusion:The clinical efficacy of perospirone hydrochloride in the treatment of schizophrenia was good,and there was no obvious adverse reactions.