稳定性心绞痛合并糖耐量异常行阿卡波糖治疗的效果

The effect of acarbose in the treatment of stable angina combine with pectoris sugar tolerance anomaly

目的:探讨稳定性心绞痛合并糖耐量异常行阿卡波糖治疗的临床效果。方法:收治稳定性心绞痛合并糖耐量异常患者120例,随机分为观察组和对照组,各60例,观察组给予阿卡波糖治疗,对照组给予常规治疗,疗程3~4年。结果:观察组心绞痛临床改善情况明显优于对照组(P<0.05)。观察组在治疗过程中,患者出现不稳定性心绞痛、心肌梗死、心力衰竭、心源性猝死以及糖尿病情况的发生率明显低于对照组(P<0.05)。结论:稳定性心绞痛合并糖耐量异常行阿卡波糖治疗可显著改善预后,能够降低心血管事件的发生率,降低糖耐量异常向糖尿病转化率。

Objective:To investigate the Clinical effect of acarbose in the treatment of stable angina combine with pectoris sugar tolerance anomaly.Methods:120 patients with stable angina combine with pectoris sugar tolerance anomaly were selected.They were randomly divided into the observation group and the control group with 60 cases in each group.The observation group were given acarbose treatment,while the control group was given conventional treatment.They were treated for 3~4 years.Results:The angina pectoris clinical improvement of the observation group was significantly better than that of the control group(P<0.05).The observation group in the course of treatment,the patients occur unstable angina,myocardial infarction,heart failure,sudden cardiac death and diabetes incidence was significantly less than those of the control group(P<0.05).Conclusion:Acarbose in the treatment of stable angina combine with pectoris sugar tolerance anomaly can significantly improve the prognosis,it can reduce the incidence of cardiovascular events,and reduce the IGT to diabetes conversion rate.