γ干扰素释放试验在肺结核早期诊断中的价值评价

To evaluate the value of γ interferon release test in early diagnosis of pulmonary tuberculosis

目的:探讨γ干扰素释放试验在肺结核患者早期诊断中的临床价值。方法:收治初次确诊为肺结核患者150例作为观察组,选择同期健康体检者60例作为对照组,对两组患者进行γ干扰素释放试验和结核菌素试验。结果:观察组在治疗前,通过γ干扰素释放试验对其进行诊断,阳性率明显高于对照组和观察组的治疗后(P<0.01);γ干扰素释放试验诊断肺结核患者的特异性与敏感性均高于结核菌素试验(P<0.01)。结论:γ干扰素释放试验在肺结核患者的早期诊断中,具有较高的敏感性和特异性。

Objective:To investigate the clinical value of γ interferon release test in early diagnosis of pulmonary tuberculosis.Methods:150 patients with pulmonary tuberculosis who were first diagnosed as the observation group,and 60 healthy subjects were selected as control group at the same time.We did γ interferon-release assays and tuberculin skin test on the two groups patients.Results:The observation group before treatment,through the γ interferon release test for the diagnosis of its,the positive rate was significantly higher than the control group and the observation group after the treatment(P<0.01); γ interferon release specific test for the diagnosis of pulmonary tuberculosis patients and the sensitivity was higher than that of tuberculin test(P<0.01).Conclusion:γ interferon release test in early diagnosis of pulmonary tuberculosis patients with high sensitivity and specificity.