肝硬化合并上消化道出血100例疗效分析

Curative effect analysis of liver cirrhosis combined with UGB in 100 cases

目的:探讨肝硬化合并上消化道出血的临床治疗。方法:收治肝硬化合并上消化道出血患者100例,随机分为观察组和对照组,各50例。两组均给予常规治疗,在此基础上,观察组给予善得定,对照组给予垂体后叶素。对比两组止血情况、治疗效果及不良反应。结果:观察组止血成功率、24 h内止血成功率显著高于对照组,止血时间明显短于对照组(P<0.05);观察组不良反应发生率18.0%显著低于对照组58.0%(P<0.05)。结论:善得定与垂体后叶素治疗肝硬化合并上消化道出血效果均较好,但垂体后叶素较易引起不良反应,而善得定止血效果和止血速度优于垂体后叶素,且不良反应发生率低。

Objective:To explore the clinical treatment of liver cirrhosis combined with UGB.Methods:100 patients with liver cirrhosis combined with upper gastrointestinal bleeding(UGB) were selected.They were randomly divided into two groups with 50 cases in each.The two groups were given conventional treatment.On this basis,the observation group was given sandostatin,and the control group was given pituitrin.The hemostasis situations,treatment effects and adverse reactions of two groups were compared.Results:The hemostasis success rate and 24 hours hemostasis success rate of the observation group were significantly higher than those of the control group,and the hemostasis time was significantly shorter than that of the control group(P<0.05).The incidence rate of adverse reaction in the observation group(18.0%) was significantly lower than 58% of the control group(P<0.05).Conclusion:Sandostatin and pituitrin in the treatment of liver cirrhosis combined with UGB all have better effect,but the pituitrin is easy to cause adverse reactions,and the hemostasis effect and hemostasis speed of sandostatin are better than those of pituitrin,and its incidence rate of adverse reaction is low.