奥氮平治疗急性期精神病患者的疗效观察

Efficacy of olanzapine in the treatment of patients with acute psychosis

目的:探讨奥氮平治疗急性期精神病患者的疗效。方法:收治急性期精神病患者39例,给予奥氮平治疗,根据PANSS量表评定治疗效果,记录不良反映。结果:与治疗前相比,患者PANSS量表评分明显降低。出现嗜睡4例、失眠3例、肌强直1例、震颤1例、体重增加10例、心动过速4例、口干3例和恶心4例。结论:奥氮平作为急性期精神病患者的治疗药物,有非常明显的效果。

Objective:To investigate the efficacy of olanzapine in the treatment of acute psychotic patients.Methods:39 acute psychosis patients were selected.They were treated with olanzapine.According to the PANSS scale,we evaluated the therapeutic effect,and we recorded the adverse reactions.Results:Compared with before the treatment,the PANSS scores of the patients were significantly decreased.There were in 4 cases of lethargy,3 cases of insomnia,1 cases of myotonia,tremor in 1 cases,10 cases of weight gain,4 cases of tachycardia,3 cases of dry mouth and nausea in 4 cases.Conclusion:Olanzapine as the drug therapy in patients with acute psychosis has significant effect.