大剂量维生素K对难治性抗凝血类鼠药中毒疗效分析

Curative effect analysis of a large dose of vitamin K in refractory anticoagulant rodenticide poisoning

目的:观察大剂量维生素K对难治性抗凝血类鼠药中毒的治疗效果。方法:收治抗凝血类鼠药中毒患者30例,分为观察组和对照组,各15例。观察组给予100~200 mg/d维生素K持续静脉滴注,对照组给予30~50 mg/d维生素K持续静脉滴注。结果:观察组总有效率100%明显优于对照组的80%(P<0.05)。结论:大剂量维生素K对难治性抗凝血类鼠药中毒的治疗效果明显。

Objective:To observe the treatment effect of a large dose of vitamin K in refractory anticoagulant rodenticide poisoning. Methods:30 patients with refractory anticoagulant rodenticide poisoning were selected.They were divided into the observation group and the control group with 15 cases in each.The observation group was given 100~200 mg/d vitamin K continuous intravenous infusion.The control group was given 30~50 mg/d vitamin K continuous intravenous infusion.Results:The total effective rate(100%) of the observation group was significantly better than 80% of the control group(P<0.05).Conclusion:A large dose of vitamin K has significant treatment effect in refractory anticoagulant rodenticide poisoning.