强化瑞舒伐他汀治疗急性冠脉综合征并行PCI治疗患者的疗效

Curative effect of rosuvastatin in the treatment of patients with acute coronary syndrome after PCI

目的:观察强化瑞舒伐他汀治疗急性冠脉综合征经皮冠状动脉介入术(PCI)患者的疗效。方法:选取60例急性冠脉综合征并行PCI术治疗的患者,平分为强化组及常规组。常规组给予瑞舒伐他汀片10 mg治疗,强化组给予瑞舒伐他汀钙20 mg治疗。对比两组血脂水平、hs-CRP、c Tn I及血CK-MB。结果:PCI术后30 d强化组的TC、TG、LDL明显比常规组降低(P<0.05)。术后24 h强化组hs-CRP明显比常规组要低(P<0.05)。强化组PCI术后围手术期心肌损伤率及心肌梗死发生率明显低于常规组(P<0.05)。结论:瑞舒伐他汀强化治疗急性冠脉综合征PCI患者可减轻术后炎性反应及围手术期心肌损伤,减少围手术期心梗发生率,从而改善患者的预后。

Objective:To observe the curative effect of rosuvastatin in the treatment of patients with acute coronary syndrome after PCI.Methods:60 cases of patients with acute coronary syndrome treated with PCI were divided into the improved group and the conventional group.The conventional group were given rosuvastatin 10 mg,and the improved group were given rosuvastatin 20 mg.The blood lipid levels,hs-CRP,c Tn I and blood CK-MB of the two groups were compared.Results:After 30 d of PCI,TC,TG,LDL of the improved group decreased more obviously than that of the conventional group(P<0.05).After 24 h of PCI,hs-CRP of the improved group decreased more obviously than that of the conventional group(P<0.05).After PCI,the incidence rate of perioperative myocardial injury and myocardial infarction of the improved group were significantly lower than those of the conventional group(P<0.05).Conclusion:Rosuvastatin in the treatment of patients with acute coronary syndrome after PCI could reduce the postoperative inflammatory reaction and perioperative myocardial injury and reduce the incidence of perioperative myocardial infarction for improving the prognosis of patients.