金城镇学龄前儿童乙肝预防接种效果分析

Effect analysis of hepatitis B vaccination of preschool children in Jincheng Town

目的:探讨金城镇学龄前儿童乙肝预防接种效果。方法:收集3~6岁儿童1 500例,进行乙肝HBs Ag、HBs Ab检测。结果:儿童HBs Ag均阴性,HBs Ab阴性率7.3%,HBs Ab阳性率92.7%。免疫程序加强与未加强儿童的HBs Ab阴性和HBs Ab阳性例数比较,差异有统计学意义(P<0.05)。年龄≤3岁和3~6岁儿童的HBs Ab阴性和HBs Ab阳性例数比较,差异有统计学意义(P<0.05)。结论:只有加强免疫史的儿童抗-HBs阳性率才达96.2%,加强和未加强免疫的免疫效果具有较大差异,年龄≤3岁及3~6岁也存在较大差异。家长或免疫接种部门应该切实按照免疫程序进行接种,尤其是加强免疫。

Objective:To explore the effect of hepatitis B vaccination of preschool children in Jincheng Town.Methods:1 500 cases of 3 to 6 years old children were selected.The HBs Ag,HBs Ab of hepatitis B were detected.Results:The HBs Ag of children were all negative.The HBs Ab negative rate was 7.3%,the HBs Ab positive rate was 92.7%.The HBs Ab negative and HBs Ab positive cases of children with immunization program reinforce and no reinforce were compared,the difference was statistically significant(P<0.05).The HBs Ab negative and HBs Ab positive cases of children with age less than or equal to 3 years old and 3 to 6 years old were compared,the difference was statistically significant(P<0.05).Conclusion:The anti-HBS positive rate of children with reinforced immunization history is 96.2%.The immune effects of reinforce and no reinforce immunization have significant difference.The age less than or equal to 3 years old and 3 to 6 years old also have significant difference.The parents or immunization vaccination department should be carried out vaccination in accordance with the immunization procedures,especially the reinforced immunization.