丙戊酸钠对于缺血性脑卒中惊厥性癫痫持续状态的治疗效果评价

Evaluation of treatment effect of sodium valproate for convulsive status epilepticus of cerebral arterial thrombosis

目的:探讨丙戊酸钠(SV)治疗缺血性脑卒中惊厥性癫痫持续状态(CSE)的效果。方法:收治CSE患者38例,采用SV治疗,观察治疗效果。结果:治疗成功24例(63.15%),4例患者发生不良反应。10例(29.4%)难治性CSE的m RS>3;实验室检查无明显恶化。结论:SV治疗缺血性脑卒中后CSE安全有效,特别是m RS低分值患者。

Objective:To explore the treatment effect of sodium valproate(SV) for convulsive status epilepticus(CSE) of cerebral arterial thrombosis.Methods:38 patients with CSE were selected.They were treated with SV.We observed the effect of treatment.Results:24 cases(63.15%) were treated successfully,and 4 cases had adverse reactions.The m RS was greater than 3 of 10patients(29.4%) with intractable CSE,and laboratory tests showed no deterioration.Conclusion:SV was safe and effective for treating CSE after cerebral arterial thrombosis,especially for patients with low m RS scores.