心理干预对使用多次胰岛素皮下注射的糖尿病患者血糖波动的影响

Influence of psychological intervention on the blood glucose fluctuation in diabetic patients with multiple insulin subcutaneous injections

目的:探讨早期心理干预对使用多次胰岛素皮下注射的糖尿病患者血糖波动的影响。方法:收治多次胰岛素皮下注射糖尿病患者300例,随机分为干预组和对照组各150例。对照组给予降糖治疗,干预组在对照组的基础上给予心理干预。两组患者治疗前后分别给予Zung自评抑郁量表、Zung自评焦虑量表、症状自评量表(SCL-90)进行测评,并观察治疗前后空腹血糖、餐后2 h血糖(2 h PG)、最高血糖与最低血糖差值(ΔMMBG)和全天平均餐后最高血糖(MPMG)。结果:治疗后干预组抑郁及焦虑评分均明显低于治疗前及对照组(P<0.05);治疗后干预组SCL-90总评分及各项评分明显低于治疗前(P<0.05);治疗后干预组空腹血糖、2 h PG、ΔMMBG、MPMG均明显低于治疗前和对照组(P<0.05)。结论:早期心理干预有助于改善使用多次胰岛素皮下注射的糖尿病患者的心理状况,提高治疗效果,减少血糖波动。

Objective:To explore the influence of early psychological intervention on the blood glucose fluctuation in diabetic patients with multiple insulin subcutaneous injections.Methods:300 diabetic patients with multiple insulin subcutaneous injections were selected.They were randomly divided into the intervention group and the control group with 150 cases in each.The control group was given hypoglycemic therapy.The intervention group was given psychological intervention on the basis of the control group.The patients in two groups were given Zung self rating depression scale,Zung self rating anxiety scale,symptom checklist(SCL-90) to evaluate before and after treatment.The fasting blood glucoses,postprandial 2 hours blood glucose(2 h PG),difference value of highest blood sugar and lowest blood sugar( Δ MMBG) and day average highest postprandial blood sugar(MPMG) were observed before and after treatment.Results:The depression and anxiety score of the intervention group after treatment were significantly lower than that before treatment and the control group(P<0.05).SCL-90 total score and each score of the intervention group after treatment were significantly lower than that before treatment(P<0.05).The fasting blood glucoses,2 h PG,ΔMMBG,MPMG of the intervention group after treatment were significantly lower than that before treatment and the control group(P<0.05).Conclusion:Early psychological intervention can improve the psychological status of diabetic patients with multiple insulin subcutaneous injections,improve the treatment effect and reduce the blood glucose fluctuation.