米力农和硝普钠在心肺功能衰竭前期手足口病患儿中的疗效对比

Comparison of curative effect of milrinone and sodium nitroprusside in early heart and lung failure of children with HFMD

目的:探讨米力农和硝普钠在心肺功能衰竭前期手足口病患儿中的疗效对比。方法:收治心肺功能衰竭前期手足口病患儿48例,随机分为两组,米力农组25例,硝普钠组23例,观察两组在控制血压、改善循环、心功能方面的疗效对比。结果:两组患儿治疗前后毛细血管再充盈时间(CRT)、收缩压(BP)、左室射血分数(EF)均有明显改变,P<0.05。结论:两者均能有效改善循环、心功能,降低血压,稳定性、安全性均较好。

Objective:To investigate the comparative efficacy of milrinone and sodium nitroprusside in heart and lung failure early of children with HFMD.Methods:48 cases of hand foot and mouth disease in children with heart and lung function failure were randomly divided into the two groups,25 cases in the milrinone group,23 cases in the sodium nitroprusside group.We observed the control of blood pressure,and the improvement of the circulation of heart function and the effect of contrast of the two groups. Results:There were significant changes in capillary refill time (CRT),systolic blood pressure(BP),left ventricular ejection fraction(EF)in the two groups of patients before and after treatment,P<0.05.Conclusion:They both can effectively improve circulation,heart function,lower blood pressure,and the stability and security are good.