摘要目的分析老年下呼吸道感染患者血清降钙素原及C反应蛋白水平,为临床判断感染性质和治疗提供参考依据。方法根据150例老年下呼吸道感染患者病情严重程度,将患者分为重度组、中度组、轻度组,分别测定三组患者的血清降钙素原(P C T)和C反应蛋白(C R P)水平并进行比较。结果随着病情加重,老年呼吸道感染患者的血清PCT及CRP含量均明显升高;呼吸衰竭组患者的PCT及CRP含量明显高于未衰竭组,差异均有统计学意义。结论可将P C T和C R P水平作为老年下呼吸道感染患者的诊断指标之一。
3N. Lagoutte,O. Facy,A. Ravoire,C. Chalumeau,L. Jonval,P. Rat,P. Ortega-Deballon.C-reactive protein and procalcitonin for the early detection of anastomotic leakage after elective colorectal surgery: Pilot study in 100 patients[J].Journal of Visceral Surgery.2012(5)
4Claudio Chiesa,Fabio Natale,Roberto Pascone,John F. Osborn,Lucia Pacifico,Enea Bonci,Mario De Curtis.C reactive protein and procalcitonin: Reference intervals for preterm and term newborns during the early neonatal period[J].Clinica Chimica Acta.2011(11)
5Raul Ruiz-Esteban,Pilar Relea Sarabia,Emilio García Delgado,Carlos Barros Aguado,Jose Amerigo Cuervo-Arango,Manuel Varela.Procalcitonin and C-reactive protein levels as diagnostic tools in febrile patients admitted to a General Internal Medicine ward[J].Clinical Biochemistry.2011(1)
6Schuetz P,Albrich WC, Mueller B. Procalcitonin for diagnosis of infec- tion and guide to antibiotic decisions:past,present and future[J].BMC Med,2011,9(1 ) : 107.
7Joo K,Park W, Lim MJ.Serum procalcitonin for differentiating bacterial infection from disease flares in patients with autoimmune diseases [J]. Korean Med Sci ,2011,26(9) :47-51.
8Arinder Malik,MBBS MD,Charles PS,et al.Beyond the Complete Blood Cell Count and C-Reactive Protein[J]. (REPRINTED)ARCH PEDIATR ADOLESC ,2010,157:511-516.
9V MANUCHA,U RUSIA,M SIKKA,MMA FARIDand N MADAN.Utility of haematological parameters and C-reactive protein in the detection of neonatal sepsis[J].Paediatr Child Health, 2002,38:459-464.