期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

非酒精性脂肪性肝病与心血管疾病机制的研究进展

下载PDF
导出
摘要 近年来,非酒精性脂肪性肝病(NAFLD)在世界范围内越来越受到关注,其定义为除酒精和其他明确的肝损伤因素所致的、以弥漫性肝细胞大泡性脂肪变为主要特征的临床病理综合征[1]。NAFLD为一系列进展性疾病谱,包括单纯性脂肪变、脂肪性肝炎、肝硬化[2],被认为是代谢综合征在肝脏的表现,同时与心血管疾病(C V D)也有密切关系[3]。关于NAFLD与CVD的相关性有许多流行病学报道,本文就N A F L D作为C V
作者 王海丽 占玉仙 赵小梅
机构地区 浙江象山县第一人民医院外科门诊 浙江大学医学院附属第一医院外科门诊
出处 《中国乡村医药》 2014年第13期78-79,74,共3页
关键词 心血管疾病 代谢综合征 脂肪性肝炎 进展性疾病 肝损伤 肝细胞 胰岛素抵抗 弥漫性 脂代谢紊乱 脂代
分类号 R575.5 [医药卫生—消化系统] R54 [医药卫生—心血管疾病]
  • 相关文献

参考文献7

  • 1Masahide Hamaguchi,Takao Kojima,Noriyuki Takeda,Chisato Nagata,Jun Takeda,Hiroshi Sarui,Yutaka Kawahito,Naohisa Yoshida,Atsushi Suetsugu,Takahiro Kato,Junichi Okuda,Kazunori Ida,Toshikazu Yoshikawa.Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease[J].World Journal of Gastroenterology,2007,13(10):1579-1584. 被引量：56
  • 2Naim Alkhouri,Tarek Abu-Rajab Tamimi,Lisa Yerian,Rocio Lopez,Nizar N. Zein,Ariel E. Feldstein.The Inflamed Liver and Atherosclerosis: A Link Between Histologic Severity of Nonalcoholic Fatty Liver Disease and Increased Cardiovascular Risk[J].Digestive Diseases and Sciences.2010(9)
  • 3G. Targher,F. Marra,G. Marchesini.Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal effect or epiphenomenon?[J].Diabetologia.2008(11)
  • 4Anna Ludovica Fracanzani,Larry Burdick,Sara Raselli,Paola Pedotti,Liliana Grigore,Gennaro Santorelli,Luca Valenti,Alessandra Maraschi,Alberico Catapano,Silvia Fargion.Carotid Artery Intima-media Thickness in Nonalcoholic Fatty Liver Disease[J].The American Journal of Medicine.2008(1)
  • 5G. Targher,L. Bertolini,S. Rodella,G. Zoppini,G. Lippi,C. Day,M. Muggeo.Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and proliferative/laser-treated retinopathy in type 2 diabetic patients[J].Diabetologia.2008(3)
  • 6Jeremy P. Domanski,Stephen J. Park,Stephen A. Harrison.Cardiovascular Disease and Nonalcoholic Fatty Liver Disease: Does Histologic Severity Matter?[J].Journal of Clinical Gastroenterology.2012(5)
  • 7Maria Stepanova,Zobair M. Younossi.Independent Association Between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease in the US Population[J].Clinical Gastroenterology and Hepatology.2012(6)

二级参考文献29

  • 1[1]Neuschwander-Tetri BA,Caldwell SH.Nonalcoholic steatohepatitis:summary of an AASLD Single Topic Conference.Hepatology 2003; 37:1202-1219
  • 2[2]Bellentani S,Saccoccio G,Masutti F,Croce LS,Brandi G,Sasso F,Cristanini G,Tiribelli C.Prevalence of and risk factors for hepatic steatosis in Northern Italy.Ann Intern Med 2000;132:112-117
  • 3[3]Browning JD,Szczepaniak LS,Dobbins R,Nuremberg P,Morton JD,Cohen JC,Grundy SM,Hobbs HH.Prevalence of hepatic steatosis in an urban population in the United States:impact of ethnicity.Hepatology 2004; 40:1387-1395
  • 4[4]Chitturi S,Farrell GC,George J.Non-alcoholic steatohepatitis in the Asia-Pacific region:future shock? J Gastroenterol Hepatol 2004; 19:368-374
  • 5[5]Akbar DH,Kawther AH.Nonalcoholic fatty liver disease in Saudi type 2 diabetic subjects attending a medical outpatient clinic:prevalence and general characteristics.Diabetes Care 2003; 26:3351-3352
  • 6[6]Gupte P,Amarapurkar D,Agal S,Baijal R,Kulshrestha P,Pramanik S,Patel N,Madan A,Amarapurkar A,Hafeezunnisa.Non-alcoholic steatohepatitis in type 2 diabetes mellitus.J Gastroenterol Hepatol 2004; 19:854-858
  • 7[7]Assy N,Kaita K,Mymin D,Levy C,Rosser B,Minuk G.Fatty infiltration of liver in hyperlipidemic patients.Dig Dis Sci 2000; 45:1929-1934
  • 8[8]Donati G,Stagni B,Piscaglia F,Venturoli N,Morselli-Labate AM,Rasciti L,Bolondi L.Increased prevalence of fatty liver in arterial hypertensive patients with normal liver enzymes:role of insulin resistance.Gut 2004; 53:1020-1023
  • 9[9]Hamaguchi M,Kojima T,Takeda N,Nakagawa T,Taniguchi H,Fujii K,Omatsu T,Nakajima T,Sarui H,Shimazaki M,Kato T,Okuda J,Ida K.The metabolic syndrome as a predictor of nonalcoholic fatty liver disease.Ann Intern Med 2005; 143:722-778
  • 10[10]Isomaa B,Almgren P,Tuomi T,Forsen B,Lahti K,Nissen M,Taskinen MR,Groop L.Cardiovascular morbidity and mortality associated with the metabolic syndrome.Diabetes Care 2001; 24:683-689

共引文献61

中国乡村医药
2014年 第13期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部