基于德温特专利数据库近10年组织工程支架、技术、假体领域的专利分析

Patent analysis of tissue-engineered scaffold, technology and prosthesis in recent decade based on Derwent Innovations Index

背景:组织工程技术为解决器官供体不足、组织创伤重建等难题提供了有效的医学手段。目的:统计和分析组织工程领域专利,全面揭示组织工程领域研发热点及核心技术,为组织工程领域相关研究人员有效利用专利信息提供信息参考。方法:以德温特专利数据库(Derwent Innovations Index)为信息来源,通过编程提取数据后,利用Excel统计数据,从专利年度分布、优先权国、专利权人、研发热点和核心专利等方面进行研究分析。结果与结论:近10年组织工程领域专利数量整体呈增长趋势,美国、中国和日本在专利申请数量上排名前3名;浙江大学、东华大学和加利福尼亚大学等学校在专利数量上排名靠前;泰科国际有限公司(TYCO HEALTHCARE GROUP LP)和强生医疗器械有限公司(ETHICON INC)两家美国公司在20项核心专利中各拥有2项且占据被引频次的前4位;美国组织工程产品引领市场;组织工程支架、组织工程技术和假体等是组织工程领域研发的热点;支架材料、细胞外基质、药物传输、构建技术和器械装置等术是组织工程领域的核心技术。

BACKGROUND: Tissue engineering technology provides an effective medical means to solve the problems of organ donor insufficiency and tissue trauma reconstruction.OBJECTIVE: To provide information reference for researchers of tissue engineering through the analysis of the patents data to grasp the hotspot and core technologies of tissue engineering.METHODS: The information including the annual distribution of patents, priority countries, patentees, hotspot of technology and core patents by Excel after extracting the data by programming based on Derwent Innovations Index.RESULTS AND CONCLUSION: In the past decade, the number of patents in the field of tissue engineering is on a rise. The most prolific countries are the United States, China and Japan. Zhejiang University, Donghua University, and the University of California are the leading institutions. Two United States companies, TYCO HEALTHCARE GROUP LP and ETHICON INC, each have two of the 20 core patents. The market of the relevant tissue-engineered products is led by the United States. Scaffolds, tissue engineering technology and prosthesis are the hot areas of tissue engineering. Scaffold materials, extracellular matrix, drug delivery, construction technology, and devices are the core technologies in the field of tissue engineering.