女性阻塞性睡眠呼吸暂停综合征患者睡眠期颏舌肌肌电的研究

Study of genioglossus myoelectricity during sleep in female patients with obstructive sleep apnea hypopnea syndrome

目的通过比较女性阻塞性睡眠呼吸暂停综合征(OSAHS)患者和健康成年女性的整夜多导睡眠监测数据和颏舌肌肌电,研究多导睡眠监测指标与颏舌肌肌电变化的关系。方法设置观察组和对照组,观察组包括符合OSAHS诊断标准的女性30例,对照组为健康成年女性30例。观察指标包括多导睡眠监测数据及颏舌肌连续表面肌电数据。结果①观察组颏舌肌肌电活性在清醒期和N3睡眠期显著增高(P<0.01),在REM期显著降低(P<0.01)。②AHI指数和最低血氧饱和度与N3期、REM期、清醒期颏舌肌肌电均相关(P<0.01)。结论女性OSAHS患者在不同的睡眠周期期颏舌肌肌电有不同的改变,且改变幅度与AHI指数及最低血氧饱和度有关。

Objective To study the relationship between polysomnographic parameters and genioglossus myoelectric changes by comparing overnight polysomnographic data and genioglossus myoelectricity in obstructive sleep apnea hypopnea syndrome(OSAHS)and healthy adult females. Methods The observation group and the control group were set up. The observation group consisted of 30 women patients(replications) who met the diagnostic criteria for OSAHS, whereas the control group consisted of 30 healthy adult women. Observation targets included polysomnography data and continuous surface EMG data of genioglossus muscle. Results ①The myoelectric activities of genioglossus in the observation group were significantly higher in the awake stage and in the N3 sleep stage, but were significantly lower in the REM stage, compared to the control group(P<0.01). ②The AHI index and the minimum oxygen saturation were correlated to the genioglossus myoelectricity in N3, REM and awake stages. Conclusion In women with OSAHS, the genioglossus myoelectric changes differently during different stages of sleep, and the magnitude of change is related to the AHI index and minimum oxygen saturation.