舒芬太尼联合咪达唑仑用于股骨上段骨折椎管内麻醉前镇痛效果观察

The Analgesic Effect Observation of Sufentanil Combined with Midazolam before Spinal Anesthesia for Femur Fracture

目的探讨舒芬太尼与咪达唑仑联用于股骨上段骨折椎管内麻醉前疼痛缓解效果。方法选取收治的股骨上段骨折患者90例,采用随机数字表法分为对照组和观察组各45例;对照组于椎管内麻醉前给予咪达唑仑;观察组在对照组基础上间隔加用舒芬太尼;比较两组椎管内麻醉前疼痛视觉模拟(VAS)评分及给药前后生命体征相关指标等。结果观察组椎管内麻醉前VAS评分明显优于对照组(P<0.05);观察组患者给药后心率、呼吸频率均明显优于对照组(P<0.05)。结论舒芬太尼与咪达唑仑联用于股骨上段骨折椎管内麻醉前疼痛缓解效果确切,可有效减轻麻醉及创伤应激反应。

Objective To investigate the analgesic effect of sufentanil combined with midazolam in spinal anesthesia before spinal anesthesia. Methods 90 patients with femur fracture were chosen and randomly divided into two groups, including control group (45 patients) with midazolam before spinal anesthesia and observation group (45 patients) with sufentanil on the basis of control group; The VAS score and related indicators of vital signs before and after treatment of both groups were compared. Res ults The VAS score before spinal anesthesia of observation group was significantly better than con-trol group(P<0.05).After treatment, the heart rate and respiratory rate of observation group were signifi-cantly shorter than control group(P<0.05). Conclusion Sufentanil combined with midazolam in spinal anesthesia before spinal anesthesia, can effectively relieve the stress reaction of anesthesia and traumat-ic.