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IGF-1、VEGF与妊娠期高血压疾病视网膜病变的相关性研究

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摘要 选取2009年6月~2012年6月我院收治的100例妊娠期高血压疾病孕妇设为观察组,其中妊娠期高血压孕妇35例,轻度子痫前期孕妇35例,重度子痫前期孕妇30例。另选同期住院待产的35例正常孕妇为对照组。观察两组孕妇IGF-1和VEGF水平的变化。结果:两组孕妇在不同孕期血清中IGF-1及VEGF水平存在显著性差异,其中观察组孕妇血清IGF-1及VEGF水平显著高于对照组正常孕妇,在视网膜病变发生率的比较中,对照组孕妇中有1例发生I级视网膜病变,而在观察组中视网膜病变的发生率更高,妊娠期高血压孕妇为45.71%,轻度子痫前期孕妇为71.43%,重度子痫前期孕妇为93.33%,其中重度子痫前期孕妇视网膜病变更为严重。血清IGF-1、VEGF水平高于正常妊娠者,与妊娠期高血压视网膜病变相关,具有预测妊高征结局的潜在价值。
出处 《现代诊断与治疗》 CAS 2014年第14期3312-3313,共2页 Modern Diagnosis and Treatment
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