急性缺血性脑卒中患者HCY水平对治疗的影响

Influence of HCY Levels in the Treatment of Acute Ischemic Stroke

目的探讨高血浆同型半胱氨酸与急性缺血性脑卒中预后的关系,为临床应用提供参考和依据。方法选取急性缺血性脑卒中患者,根据血浆同型半胱氨酸(HCY)浓度高低分成高HCY组和HCY正常组,每组60例,对两组患者进行常规治疗。对两组患者的治疗效果进行观察分析。结果治疗后,高HCY组治疗总有效率78.3%,显著低于HCY正常组(90.0%),且差异具有统计学意义(P<0.05);两组患者均无严重并发症发生。结论高同型半胱氨酸血症会导致急性缺血性脑卒中患者预后不佳,在治疗和护理工作中应首先进行HCY测定,并采取相应的措施,尽量改善患者的预后,提高治疗有效率。

Objective To investigate the relationship of high plasma homocysteine and prognosis of acute ischemic stroke. Methods Patients with acute ischemic stroke were selected, and according to HCY levels, patients were divided into high HCY group and normal HCY group, 60 cases in each groups. Patients were treated with conventional treatment. The efficacy of two groups were analyzed. Results After treatment,to-tal effective rate of high HCY group was 78.3%,which was significantly lower than normal HCY group (90.0%),the difference was statistically significant (P<0.05). Conclusion High homocysteine result poor prognosis of acute ischemic stroke patients,and appropriate measures should be carried.