比较布托啡诺和舒芬太尼术后患者自控静脉镇痛的临床效果

Compariso n of the Clinical Effect of Butorphanol and Sufentanil Postoperative Patient Controlled Intravenous Analgesia

目的：观察布托啡诺和舒芬太尼术后患者自控静脉镇痛（PCIA）的临床效果，并探讨其不良反应。方法取2013年5月~2014年3月我院收治的60例剖宫产手术患者，本组患者均行PCIA，随机均分为A、B、C三组各20例。A组应用布托菲诺；B组应用托烷司琼和舒芬太尼；C组应用托烷司琼、布托菲诺、舒芬太尼联合镇痛。观察三组术后镇静镇痛效果评分、HR、BP、SpO2，统计三组不良反应发生率。结果与A组相比，B、C两组镇痛效果更优，组间差异具有统计学意义（P＜0.05）；C组镇静评分更高，但与A、B组相比差异并无统计学意义（P＞0.05）；三组患者不良反应发生率差异无统计学意义（P＞0.05）。结论对于剖宫产患者而言，单纯给予布托菲诺往往难以收到满意的术后镇痛效果，联用舒芬太尼则可有效镇痛，且较少不良反应，值得临床推广使用。

Objective To observe clinical effect of butorphanol and sufentanil in postoperative patient controlled intravenous analgesia(PCIA),and explore the adverse reactions. Methods 60 cases of cesare-an surgery patients(PCIA)in our hospital from May 2013 to March 2014, were randomly divided into 3 groups,20 cases of each group. Group A was given Bhutto Fino; Group B was given tropisetron and sufentanil; Group C was given tropisetron, Bhutto Fino, sufentanil joint pain. Postoperative analgesia sedation score, HR, BP and SpO2 in three groups were observed. Incidence in three groups of adverse reactions were analyzed. Results Compared with group A, group B, C had better analgesic effect,there was statistical significance (P<0.05);Group C sedation score was higher,but compared with A, there was no statistical significance (P>0.05); The incidence of adverse reactions in 3 groups was no signifi-cant difference(P>0.05). Conclusion For cesarean section patients, simply giving Bhutto Fino is often difficult to receive satisfactory effect of postoperative analgesia, it can be effectively combined with sufentanil analgesia and fewer adverse reactions, worthy of clinical use.