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短期双分割伽玛刀治疗大型脑转移瘤的临床结果分析

Analysis of Short-term Clinical Outcome Double Split Large Gamma Knife Treatment of Brain Metastases
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摘要 目的 探讨大型脑转移瘤患者行短期双分割伽玛刀治疗的疗效及预后情况.方法 回顾性分析了2006年1月至2011年12月在我院行短期双分割伽玛刀治疗的52例大型脑转移瘤患者,总剂量20~28Gy,2w内分2次完成,等剂量曲线45%~50%.结果 中位随访时间为10个月.1年和2年生存率分别为45%和21%.中位生存期为11.5个月.6和12个月局部控制率为83%和60%.平均KPS评分第1次伽玛刀时为71,第2次伽玛刀时提高到83.3例病人(6%)出现了放射性损伤的症状经保守治疗后好转.结论 长期随访显示短期双分割伽玛刀肿瘤控制率高治疗相关死亡率低,是大型脑转移瘤特别是一般情况较差患者较合理的治疗选择.
出处 《现代诊断与治疗》 CAS 2014年第22期5068-5071,共4页 Modern Diagnosis and Treatment
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