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探讨厄贝沙坦联合氢氯噻嗪治疗老年原发性高血压的疗效及对心肾功能的影响 被引量:7

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摘要 目的研究厄贝沙坦联合氢氯噻嗪治疗老年原发性高血压的疗效及对心肾功能的影响。方法选择就诊的高血压患者100例,按随机数字表法分为对照组及观察组。对照组采用厄贝沙坦,观察组采用厄贝沙坦联合氢氯噻嗪治疗,两组均治疗6个月。观察两组血压、不良反应发生率,检测血尿素氮(BUN)、血清肌酐(Scr)、内生肌酐清除率(Ccr)、左心室质量及左心室质量指数。结果观察组治疗后血压降低幅度更大(P<0.05);观察组治疗后Ccr提高幅度及BUN、Scr降低幅度更大(P<0.05);观察组治疗后左心室射血分数及6min步行试验升高幅度更大(P<0.05);两组均未发生严重不良反应。结论厄贝沙坦联合氢氯噻嗪治疗老年原发性高血压降压效果较好,可改善心肾功能。
出处 《现代诊断与治疗》 CAS 2019年第11期1829-1831,共3页 Modern Diagnosis and Treatment
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