抗疏强骨合剂对高龄髋部骨折手术患者治疗效果的临床研究

Clinical study on the Therapeutic Effect of Anti-osteoporosis and Bones Strengthening Mixture on Elderly Patients with Hip Fracture Operation

目的观察抗疏强骨合剂对髋部骨折手术患者的临床效果。方法收集2016年3月~2018年4月收治284例(年龄≥75岁)髋部骨折手术患者临床资料,治疗组:手术结合抗疏强骨合剂与对照组:单纯手术治疗。其中PFNA96例(对照组48例,治疗组48例)、DHS60例(对照组28例,治疗组32例)、THA128例(对照组60例,治疗组68例),比较相同治疗方案下对照组与治疗组的治疗效果、手术相关指标、术后并发症、髋部功能评分及死亡率。结果治疗组手术出血量少于对照组(P<0.05);治疗手术时间少于对照组,但差异无统计学意义(P>0.05);卧床时间、负重时间治疗组均小于对照组(P<0.05);术后1年并发症各指标中治疗组血栓及假体松动率优于对照组(P<0.05),感染率死亡率无临床差异(P>0.05);术后髋关节功能治疗组优于对照组(P<0.05)。结论结合临床大样本资料分析抗疏强骨合剂对高龄髋部手术患者,可减少出血量、缩短患肢负重天数,减少术后血栓发生率及假体松动,使髋关节功能恢复更理想。

Objective:To observe the therapeutic effect of Anti-osteoporosis and Bones Strengthening Mixture on elderly patients with hip fracture operation.Methods:Clinical data of 284 patients with hip fracture treated from March 2016 to April 2018 were collected.The experimental group:surgery combined with Anti-osteoporosis and Bones Strengthening Mixture and blank group:surgery alone;The experimental group included 96 cases of PFNA(48 cases in blank group,48 cases in experimental group),60 cases of DHS(28 cases in blank group,32 cases in experimental group)and 128 cases of THA1.(60 cases in blank group and 68 cases in experimental group)The therapeutic effect,operative related indexes,postoperative complications,hip function score and mortality were compared between blank group and experimental group under the same treatment regimen.Results:The amount of bleeding during operation in the experimental group was less than that in the blank group(P<0.05);the operation time in the experimental group was less than that in the blank group,but there was no significant difference(P>0.05);the bed-rest time and weight-bearing time in the experimental group were less than that in the blank group(P<0.05);the thrombus and prosthesis loosening rate in the experimental group was better than that in the blank group one year after operation.There was no clinical difference in infection rate and mortality rate(P>0.05),and the experimental group of hip joint function after operation was better than the blank group(P<0.05).Conclusion:Combining with large clinical sample data,Anti-osteoporosis and Bones Strengthening Mixture can reduce the amount of bleeding,shorten the days of weight-bearing of affected limbs,reduce the incidence of thrombosis and loosening of prosthesis,and make the recovery of hip joint function more ideal.